You have arrived at the web site for Eric Accili’s Laboratory at the University of British Columbia. We study ion channel proteins hence canal ionique, which is french for ion channel. We are mainly interested in ion channels that sense changes in voltage, electricity that is generated by the movement of ions such as potassium and sodium. Voltage-sensitive ion channels reside at the surface of cells and, by controlling the movement of ions, coordinate electrical activity to regulate functions such as contraction rate and strength in cells of the heart or electrical conduction in nerves of the brain.